Targeting transdifferentiated hepatic stellate cells and monitoring the hepatic fibrogenic process by means of IGF2R-specific peptides designed <i>in silico</i>

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چکیده

In silico designed peptides showed high binding affinity towards activated human hepatic stellate cells, offering new strategies to target insulin-like growth factor 2 receptor in fibrotic liver and suggesting a potential for noninvasive diagnosis.

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ژورنال

عنوان ژورنال: Journal of Materials Chemistry B

سال: 2021

ISSN: ['2050-7518', '2050-750X']

DOI: https://doi.org/10.1039/d0tb02372h